Illumina stock fell 1.42 percent to USD 270.00 on September 25, 2026

Published on 09/28/2026 at 12:15 | Editorial responsibility: Rafael Müller, Editor-in-Chief AD HOC NEWS

Illumina stock carried a USD 40.8 billion valuation at the September 25, 2026 close. UBS raised its target to USD 260.00 on September 9.

Schwarzweiß-Reportagefoto einer Wissenschaftlerin beim Pipettieren im Genomiklabor — Illumina Inc. zeigt US4523271090 in dokumentarischer Schwarzweiß-Reportage einer Wissenschaftlerin beim Pipettieren im Labor, Illustration mit AI erstellt.

Illumina stock (ISIN US4523271090) fell 1.42 percent to USD 270.00 at the Nasdaq close on September 25, 2026. The move followed a sharp September advance, while UBS had raised its price target from USD 135.00 to USD 260.00 on September 9, 2026.

UBS doubles its price target

According to MarketBeat on September 9, 2026, UBS upgraded Illumina from Neutral to Buy and lifted its target from USD 135.00 to USD 260.00. The new target stands 25.93 percent below the September 25 closing price, making the broader analyst view important for investors assessing valuation.

MarketBeat reported on September 12, 2026, that 18 brokerages held a consensus rating of Hold, with 10 Buy ratings, six Holds and two Sells. The average 12-month target was USD 199.13, below the UBS target and the closing share price.

Revenue rises in Q2 2026

Illumina reported USD 1.16 billion in Q2 2026 revenue, up 9.4 percent from the same quarter a year earlier, according to MarketBeat. Adjusted EPS was USD 1.31 versus a USD 1.23 consensus estimate, while fiscal 2026 EPS guidance stood at USD 5.30-5.40.

The company has also set a higher operating base for the year. The Q2 revenue comparison and the adjusted EPS beat give the stock a fundamental counterweight to its elevated valuation, although the consensus target remains below the market price.

Stock remains near its yearly high

Illumina's September 25 market capitalization was USD 40.8 billion, with trading volume of 5.03 million shares. The close was USD 7.95 below the 52-week high of USD 277.95 and USD 182.00 above the 52-week low of USD 88.00.

The company was added to the S&P 500, with the Nasdaq listing and ISIN US4523271090 confirmed by MarketScreener on September 20, 2026. That index status adds a structural market factor alongside earnings growth and analyst revisions.

September 25 close sets the reference

Illumina stock closed at USD 270.00 on Nasdaq on September 25, 2026, down 1.42 percent from USD 273.90, with a session high of USD 276.97 and a low of USD 267.66.